Biology and Pathology of the Oocyte Trounson Gosden Eichenlaub-Ritter 2e

Description: Biology and Pathology of the Oocyte Role in Fertility, Medicine and Nuclear Reprograming This new edition covers the development, biology and pathology of the oocyte, and technologies to manipulate, enhance and control fertility. Alan Trounson (Edited by), Roger Gosden (Edited by), Ursula Eichenlaub-Ritter (Edited by) 9781107021907, Cambridge University Press Hardback, published 24 October 2013 466 pages 25.2 x 19.8 x 2.5 cm, 1.2 kg The human egg - the rarest and most rapidly aging cell in the body - is a topic of intense scientific study. Assisted reproduction clinics are constantly vying to improve success rates - choosing the best gametes is a key step in this process. This new edition of what one reviewer of the first edition described as 'possibly the definitive work on the oocyte' covers the development, biology and pathology of the oocyte, and technologies to manipulate, enhance and control fertility. These technologies are used to overcome infertility, avoid inherited diseases, and create genetically engineered embryos from stem cells and cloning. This progress would have been impossible without the myriad of scientific and technical developments covered in this book. The new edition is thoroughly updated and includes major new research on reprogramming, oocyte molecular development, cryopreservation and viability. We are in exciting times for the egg. Preface Part I. Historical Perspective: 1. Insights into the amphibian egg to understand the mammalian oocyte Kei Miyamoto and John B. Gurdon Part II. Life Cycle: 2. Otogeny of the mammalian oocyte Anne Grete Byskov and Majken Nielsen 3. Gene networks in oocyte meiosis Paula Cohen and Swapna Mohan 4. Follicle formation and oocyte death Melissa E. Pepling 5. The early stages of follicular growth Alain Gougeon 6. Follicle and oocyte developmental dynamics Aaron J. W. Hsueh and Kazuhiro Kawamura 7. Mouse models to identify genes throughout oogenesis Jia Peng, Qinglei Li and Martin M. Matzuk Part III. Developmental Biology: 8. Structural basis for oocyte-granulosa cell interactions Ursula Eichenlaub-Ritter and Carlos Plancha 9. Differential gene expression mediated by oocyte/granulosa cell communication Saiichi Furukawa and Koji Sugiura 10. Hormones and growth factors in the regulation of oocyte maturation Marco Conti 11. Getting into and out of oocyte maturation Hayden Homer 12. Chromosome behavior and spindle formation in mammalian oocytes Heide Schatten and Qing-Yuan Sun 13. Transcription, accumulation, storage, recruitment, and degradation of maternal mRNA in mammalian oocytes Santhi Potireddy, Dasari Amarnath and Keith E. Latham 14. Setting the stage for fertilization: transcriptome and maternal factors Scott Coonrod 15. Egg activation: initiation and decoding of Ca2+ signalling John Carroll and Karl Swann 16. In vitro growth and differentiation of oocytes Hang Yin and Roger Gosden 17. Metabolism of the follicle and oocyte in vivo and in vitro Helen M. Picton and Karen E. Hemmings 18. Improving oocyte maturation in vitro Jeremy G. Thompson and Robert B. Gilchrist Part IV. Imprinting and Reprogramming: 19. Human genes modulating primordial germ-cell and haploid gamete formation Valerie L. Baker, Ruth Lathi and Renee A. Reijo Pera 20. In vitro differentiation of germ cells from stem cells Fumihiro Sugawa, Karin Hübner and Hans R. Schöler 21. Parthenogenesis and parthenogenetic stem cells Tiziana A. L. Brevini and Fulvio Gandolfi 22. Epigenetic consequences of stomatic cell nuclear transfer and induced pluripotent stem cell reprogramming Jose Cibelli, Victoria L. Mascetti and Roger A. Pedersen 23. Primate and human somatic cell nuclear transfer Rita P. Cervera and Shoukhrat Mitalipov Part V. Pathology: 24. Gene expression in human oocytes Gayle M. Jones and David S. Cram 25. Omics as tools for oocyte selection Marc-André Sirard and Isabelle Gilbert 26. The legacy of mitocondrial DNA Helen A. L. Tuppen, Mary Herbert and Doug M. Turnbull 27. Relative contribution of advanced age and reduced follicle pool size on reproductive success: the quantity-quality enigma Frank Broekmans and Madeleine Dólleman 28. Cellular origin of age-related aneuploidy in mammalian oocytes Ursula Eichenlaub-Ritter and Roger Gosden 29. Alterations in the gene expression of aneuploid oocytes and associated cumulus cells Dagan Wells 30. Transgenerational risks by exposure in utero Miguel A. Velazquez and Tom P. Fleming 31. Obesity and oocyte quality Rebecca L. Robker and Robert J. Norman 32. Safety of ovarian stimulation Dominic Stoop, Ellen Anckaert and Johan Smitz 33. Oocyte epigenetics and the risks for imprinting disorders associated with assisted reproduction Serge McGraw and Jacquetta Trasler 34. Genetic basis for primary ovarian insufficiency Luca Persani, Stephanie Sherman and Lawrence Nelson Part VI. Technology and Clinical Medicine: 35. Polar body screening for aneuploidy in human oocytes Luca Gianaroli, M. Christina Magli and Anna P. Ferraretti 36. Cytopreservation of oocytes Alan Trounson and Laura Rienzi 37. Transplantation of ovarian tissue or immature oocytes to preserve and restore fertility in humans Sherman Silber, Natalie Barbey and David Silber Index. Subject Areas: Gynaecology & obstetrics [MJT], Infertility & fertilization [MFKC1], Reproductive medicine [MFKC], Medicine [M]

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